BioMed PartnersDiscuss ProxiGene ↗

PROXIGENE PGx · PHARMACOGENOMICS

ProxiGene PGx

Genetic insights for prescribing decisions.

ProxiGene PGx is a provider-ordered pharmacogenomics panel that translates inherited variation into a structured, clinically oriented report. BioMed Partners connects practices and health systems with the HealthSpan360 team to explore implementation.

First page of the ProxiGene provider overview, showing coverage and the clinician decision support features
Explore the provider overview below.
34genes, HLA loci & pharmacodynamic markers
14therapeutic categories
1buccal swab, provider ordered

FROM SAMPLE TO ACTION

Designed for the clinical decision.

01

Order & collect

The ordering clinician requests the panel and a buccal swab is collected for laboratory analysis.

02

Analyze & interpret

The assay evaluates selected metabolism, transporter, HLA and pharmacodynamic markers. Results are interpreted with reference to CPIC, DPWG, FDA and PharmGKB resources.

03

Review & apply

A clinician action summary prioritizes major and moderate findings, followed by therapeutic assessments, genotype details, methods and citations. The prescriber considers the result alongside the full clinical picture.

WHAT MAKES THE REPORT USEFUL

See the action first. Inspect the evidence beneath it.

Severity-ranked findings

Potential gene–drug interactions are triaged with drug or dose considerations where the report supports them.

Transparent scope

Diplotype and phenotype calls, including no-action findings, accompany the list of alleles interrogated.

Evidence with context

Findings are organized by therapeutic area and include guideline or labeling references to support clinician review.

POTENTIAL CLINICAL APPLICATIONS

Relevant across specialties.

Primary care: clopidogrel, statins, antidepressantsPsychiatry: antidepressants & antipsychoticsCardiology: clopidogrel, warfarin & statinsPain & anesthesia: codeine, tramadol & selected risk markersOncology: fluoropyrimidines, thiopurines & irinotecanGastroenterology, infectious disease & neurology

Examples illustrate gene–drug areas included in the source materials; a result does not determine treatment on its own.

PROVIDER MATERIALS

Explore the full ProxiGene package.

Review the PGx overview and provider presentation, then discuss ordering and clinical workflow with our team.

ProxiGene PGx Panel is a HealthSpan360 product and a provider-ordered laboratory-developed test performed in a CLIA-certified laboratory (CLIA #45D2326543). It is not FDA cleared or approved. It evaluates variants included in the assay and informs, rather than replaces, the prescriber’s clinical judgment. Confirm current test documentation, ordering requirements and applicability with HealthSpan360.